Advances and Progress in Drug Design  15th February to 16th February 2016, London, United Kingdom

SMi presents the 15th Annual Advances and Progress in Drug Design 2016, with a strong focus on advanced biophysical technologies and combinatorial methods enabling greater insight of biologics and drug interaction. 
Hosted over two days, this international conference will provide an exclusive opportunity to gain new insight on small molecule-protein fragments, IMI Open PHACTS project for data mining work flows, and structure-based models combining hit finding strategies of fragment leads.
Inspiring talks will also highlight developments in the quality control of misfolded proteins, solvent effects, and protein-ligand stability; identifying whether the bound conformation of protein-ligand structure gives the lowest energy state and the impact of drug design.

Join us for a keynote address on reviving covalent drug design in oncology from Pfizer, and a case study session on target validation of NCE’s through fragment screening and opportunities for antibodies as guidance tools from UCB.

MacroBeGe 2016 3rd Belgian-German Macromolecular Meeting Houffalize, Belgium - February 15-16, 2016

Advances and Progress in Drug Design  15th February to 16th February 2016, London, United Kingdom

SMi presents the 15th Annual Advances and Progress in Drug Design 2016, with a strong focus on advanced biophysical technologies and combinatorial methods enabling greater insight of biologics and drug interaction. 
Hosted over two days, this international conference will provide an exclusive opportunity to gain new insight on small molecule-protein fragments, IMI Open PHACTS project for data mining work flows, and structure-based models combining hit finding strategies of fragment leads.
Inspiring talks will also highlight developments in the quality control of misfolded proteins, solvent effects, and protein-ligand stability; identifying whether the bound conformation of protein-ligand structure gives the lowest energy state and the impact of drug design.

Join us for a keynote address on reviving covalent drug design in oncology from Pfizer, and a case study session on target validation of NCE’s through fragment screening and opportunities for antibodies as guidance tools from UCB.

11th Protein Kinases in Drug Discovery Conference February 29 - March 1, 2016, San Diego, CA

We invite you to attend the 11th Protein Kinases in Drug Discovery Conference, which will take place February 29 - March 1, 2016 in San Diego, CA.

Over the past decades, protein kinases have proven to be an important class of drug targets for the pharmaceutical industry. This meeting seeks to create a forum for scientists from both industry and academia to gather and discuss the most recent advances in kinase inhibitor research. Leading researchers will present on hot topics such as reversible and irreversible inhibitors, kinome selectivity and translation, kinase evolution and resistance, and many more. In addition to scientific talks, dedicated networking sessions will allow attendees to better dialogue on how kinase inhibitor discovery will continue to expand.

Sessions include:
I. Novel Approaches in Kinase Targeting
II. New Tools and Technologies in Kinase Drug Discovery
III. Kinome Selectivity and Translation to Clinical Safety
IV. Kinase Evolution & Development of Resistance to Kinase Inhibitors

Conference Dates: February 29 - March 1, 2016

https://www.gtcbio.com/conferences/protein-kinases-drug-discovery-overview

6th Ubiquitin Research & Drug Discovery Conference February 29 - March 1, 2016, San Diego, CA

We are pleased to invite you to GTCbio's 6th Ubiquitin Research & Drug Discovery Conference, which will take place February 29 - March 1, 2016 in San Diego, CA. This conference will provide a forum for researchers from industry and academia to learn about recent advances in basic science and drugs that target the ubiquitin/proteasome system. Hot topics such as autophagy in cancer, developments with deubiquitinating enzymes, and novel drug targets in the ubiquitin system will be covered.

Please join us not only for updates on the latest scientific research, but also for networking sessions between colleagues from both industry and academia in order to get the most comprehensive exchange of ideas.

Session Topics:

1. Advances in Ubiquitin-like Modifications
2. Ubiquitin Pathways in Neurodegenerative Disorders
3. Ubiquitin Proteasome System & Oncology
4. Autophagy in Cancer & Metabolic Diseases
5. Novel Drug Targets in the Ubiquitin System
6. Deubiquitinating Enzymes as Drug Targets

Conference Dates: February 29 - March 1, 2016

https://www.gtcbio.com/conferences/ubiquitin-research-drug-discovery-overview

Enzymes in Drug Discovery Summit February 29 - March 2, 2016, San Diego, CA

We are excited to announce the Enzymes in Drug Discovery Summit, which will take place February 29 - March 2, 2016 in San Diego, CA.

Enzymes have proven to be an important group of drug targets in diseases, and enzyme inhibitors have been among the most successful of drugs. Join us as we discuss ways to overcome drug resistance to these inhibitors, and discuss breakthroughs in targeting historically undruggable enzymes.

This summit will feature the following four conferences:

11th Protein Kinases in Drug Discovery
I. Novel Approaches in Kinase Targeting
II. New Tools and Technologies in Kinase Drug Discovery
III. Kinome Selectivity and Translation to Clinical Safety
IV. Kinase Evolution & Development of Resistance to Kinase Inhibitors

6th Ubiquitin Research & Drug Discovery

I. Advances in Ubiquitin-like Modifications
II. Ubiquitin Pathways in Neurodegenerative Disorders
III. Ubiquitin Proteasome System & Oncology
IV. Autophagy in Cancer & Metabolic Diseases
V. Epigenetic Novel Drug Targets in the Ubiquitin System
VI. Deubiquitinating Enzymes as Drug Targets

2nd Protease Inhibitors in Drug Discovery

I. Membrane-Associated Systems
II. Medical Chemistry & Drug Design of Protease Inhibitors
III. Non-Active Site Inhibition of Proteases
IV. Protease Inhibitors in Translational Research
- Cardiovascular System
- Infectious Diseases
- Inflammatory Diseases
- Neurodegenerative Diseases
- Musculoskeletal Diseases

Epigenetic Enzymes in Drug Discovery

I. Epigenetic Modification & Transcriptional Regulation
II. Pre-Clinical to Clinical Drug Development
III. Immunotherapy: Conversion of Mechanisms
IV. Translating & Combining Antibodies
V. Novel Therapeutic Targets and Discovery

We encourage you to sign up for a summit pass in order to get the most comprehensive look at research and drug discovery happening in the field. In addition to scientific presentations, dedicated networking sessions will allow you to connect and form new relationships with different people in the field and from both the private and public sector.

We hope to see you there!

Conference Dates: February 29 - March 2, 2016

https://www.gtcbio.com/conferences/enzymes-drug-discovery-summit-overview