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BioScreening - organic compounds for screening
HIV ResearchHTLV blood screening test from RTP diagnostics firm Avioq gets FDA OK - The U.S. Food and Drug Administration has approved a new test for blood donations, just the second test available to screen for two viruses linked to leukemia and neurologic disorders. The blood test, developed by medical device company Avioq, detects antibodies to human T-lymphotropic virus type 1 (HTLV 1) and human T-lymphotropic virus type 2 [...]
LABS, Inc. Launches Suite of Next-Generation Test Offerings; Focuses on Expanding Complex Biologic Testing Portfolio in 2012 - CENTENNIAL, Colo., March 21, 2012 /PRNewswire via COMTEX/ — LABS, Inc., a global, full-service testing laboratory with more than 30 years of expertise in regulated testing for human organs, cells, tissues and implantable biologic products and devices, this month launches a group of new laboratory tests suitable for screening complex biologic products. These new offerings [...]
Research at A&M and Scripps finds HIV-killing compound - COLLEGE STATION - A powerful topical preventative for HIV, the virus that causes AIDS, could be a step closer to clinical trials, thanks to a newly discovered molecular compound that research at Texas A&M University and the Scripps Research Institute shows dissolves the virus on contact. The ability of the synthetic compound known as “PD 404,182″ [...]
Body & Mind – HEALTH U.S. Doctor Cautious About HIV Vaccine - A New York City-based infectious disease specialist said a new vaccine developed by Spanish scientists, which could turn HIV into minor infection status, is reason to be cautiously optimistic. Dr. Joseph Rahimian said Thursday news of an HIV vaccine is certainly exciting, but questions remain. “An HIV vaccine has been the holy grail for infectious [...]
Daily pill can prevent HIV infection - The partners of people who have HIV can protect themselves from infection by taking a once-daily pill, two groundbreaking studies in Botswana, Kenya and Uganda have shown. The discovery could bring work to combat Aids close to a “tipping point”, experts say. Attempts to promote condom use to protect against HIV in the hardest-hit parts [...]
Hemophilia Is Target of Therapy on Genome - Researchers using a new technique for editing the genome of living cells have shown that they can cure hemophilia in mice, at least in principle, with a couple of injections that carry out the “cut” and “paste” operations needed to insert a corrective gene. This is the first time this genome-editing technique has succeeded in [...]
Premature aging seen as issue for AIDS survivors - SAN FRANCISCO (AP) — Having survived the first and worst years of the AIDS epidemic, when he was losing three friends to the disease in a day and undergoing every primitive, toxic treatment that then existed, Peter Greene is grateful to be alive. But a quarter-century after his own diagnosis, the former Mr. Gay Colorado, [...]
FDA Okays New HIV Drug - WASHINGTON — The FDA has approved rilpivirine (Edurant) for the treatment of HIV patients who have not yet begun therapy. The drug, a non-nucleoside reverse transcriptase inhibitor, is intended to be used as part of highly active anti-retroviral therapy (HAART) with at least two other medications, the agency said. Rilpivirine, also known as TMC278, is [...]
Trana Discovery’s HIV Assay Finds Compounds that Inhibit NNRTI and Multi-Drug Resistant HIV Viruses - Trana Discovery, Inc., an infectious disease drug discovery technology company, today announced that a recent study sponsored by the National Institute of Allergy and Infectious Disease, part of the National Institutes of Health, affirms that bioactive compounds selected using the Trana HIV 201 High-Throughput (HTS) Assay inhibit viral strains demonstrating resistance to non-nucleoside reverse transcriptase [...]
AIDS Drugs – HIV - In the early 1980s, the human immunodeficiency virus (HIV) was identiÂfied as the etiologic agent of acquired immune deficiency syndrome (AIDS). More than 3 million people worldwide died from HIV/AIDS in 2003, according to a July 2004 United Nations report. During the same period, about 5 million people contracted the human immunodeficiency virus, bringing the [...]
Trana Discovery and Southern Research Institute Find Bioactive HIV Antiviral Compounds: NIAID contracts additional $700,000 to screen 300,000 more compounds for HIV inhibition - Trana Discovery and Southern Research Institute Find Bioactive HIV Antiviral Compounds: NIAID contracts additional $700,000 to screen 300,000 more compounds for HIV inhibition PRNewswire – October 28, 2009 CARY, N.C. and BIRMINGHAM, Ala., Oct. 28 /PRNewswire-USNewswire/ — Trana Discovery, Inc., an infectious disease drug discovery technology company, and Southern Research Institute, a not-for-profit contract research [...]
Researchers find candidates for new HIV drugs - While studying an HIV protein that plays an essential role in AIDS progression, researchers at the University of Pittsburgh School of Medicine have discovered compounds that show promise as novel treatments for the disease. HIV drug discovery efforts have met with little success in finding compounds that interact with an important HIV virulence factor, called [...]
Progress in Finding a New Class of HIV Drugs - Scientists have discovered a method for screening an entirely new class of drugs, targeted against the HIV protein Nef, according to an article published online October 6 in ACS Chemical Biology and reported by ScienceDaily. HIV’s Nef protein has an important indirect influence on how well HIV functions in the body. The presence of Nef [...]
AIDS Study Flushes Out Hidden Virus, Pointing to Possible Cure - Oct. 2 (Bloomberg) — Scientists, moving closer to a cure for AIDS, identified a way to find medicines that would help rid patients of the hardest-to-treat pockets of HIV. Current anti-HIV drugs reduce the virus to undetectable levels without eradicating it. The virus survives by lying dormant in immune-system cells, where the medicines don’t reach [...]
Virtual Screening Gives Drug Design a Boost - San Diego, CA (OBBeC) – Researchers at the University of California, San Diego, developed a unique computational approach to identify key compounds that could lead to new drugs to combat African sleeping sickness — a disease spread by the biting tsetse fly and caused by the parasite Trypanosoma brucei. Around 150,000 people per year get [...]
Seegene/Lab901 brings a New Detection Platform for Multiple Pathogens to European Hospitals - Rockville, MD, and Edinburgh, Scotland, June 17, 2008:Â Seegene and Lab901 today announced the availability of a novel automated multi-pathogen walk-away detection platform for European hospitals. Based on the Seeplex(R) multiplexing PCR system and ScreenTape(R)Â gel electrophoresis detection system, this new Seeplex/ScreenTape detection platform will be introduced to clinical and research laboratories in 10 countries [...]
Validated biomarkers will drive personalized medicine - Biomarkers will be accepted as predicted tools, but their clinical usefulness needs to be understood first, according to personalized medicine expert. Coordinating personalized medicine on an international level, Dr Edward Abrahams, Executive Director of the Personalized Medicine Coalition believes that biomarkers will eventually impact all disease areas. “When they were validated, and when it can [...]
Health Care’s Silent Spring - As the Intergovernmental Working Group (IGWG) of the WHO prepares to meet and discuss how to best facilitate the expropriation of intellectual property rights (in this case the IPR of pharmaceutical patents) it’s important to consider the unintended consequences — the death of medical innovation. The global purloiners of patents — led by Jamie Love [...]
ViroStatics Establishes Scientific Advisory Board for HIV Development Program - SASSARI, Italy & PRINCETON, N.J. – (Business Wire) ViroStatics, srl, a privately-held pharmaceutical company focused on the discovery and development of combination therapeutics in HIV/AIDS, virology, and other chronic diseases, today announced the formation of a Scientific Advisory Board (SAB). Chaired by Daniel Kuritzkes, MD, Director of AIDS Research, Brigham & Women’s Hospital in Boston, [...]
SRI helps develop screening program for AIDS drugs - Research conducted at Birmingham’s Southern Research Institute helped develop a system to identify drugs with the ability to fight the virus that causes AIDS. Trana Discovery, a North Carolina-based drug discovery technology company, worked with Southern Research to create a screening system to identify drugs that inhibit HIV replication. The system can be used by [...]
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