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BioScreening - organic compounds for screening
HT Screening NewsSpermatech Selects Evotec as Partner for High-Throughput Screening and Lead Discovery - HAMBURG, Germany and OXFORD, England and OSLO, March 12, 2008 /PRNewswire-FirstCall/ — Evotec AG announced today that Spermatech A/S has chosen them as a partner to identify small molecule therapeutics for their pharmaceutical discovery project.
Through the study of the physiology of sperm motility, more specifically of “rapid swimmers” that cause fertilisation, Spermatech have identified biological [...]
US Plans Use of Automated Toxicity Screening, Could End Animal Testing - Federal scientists are collaborating on a new approach to testing the toxicity of chemicals ranging from pesticides to household cleaners. They plan to use new automated high-speed cell tests to get more reliable data faster and more cheaply, and with less reliance on animal testing.
The National Institutes of Health and the U.S. Environmental Protection Agency are partners [...]
High Throughput Screening 2007: HighTech Business Decisions Reports New Strategies, - SAN JOSE, Calif.--(Business Wire)--HTS laboratories continue to evolve their processes and strategies
to increase their success rates and improve efficiencies in their drug
discovery efforts. New strategies include the use of phenotypic and
pathway-based assays in primary or secondary screening, the use of new
targets and the expansion in the diversity of compounds screened for
new drug candidate leads. The [...]
Burnham Institute Selects Labcyte Acoustic Liquid Handling Technology - Sunnyvale, CA November 15, 2007 - Labcyte Inc. will supply Burnham Institute for Medical Research (Burnham) with more than $2.3 million worth of Echo® liquid handlers for use in screening large biological libraries. The systems will be installed at both the Institute’s LaJolla, (CA) and Lake Nona, Orlando (FL) campuses. These instruments will be part [...]
Researchers from Novartis have published results using high-throughput screening (HTS) mass spectrometry (MS) techniques for the identification of enzyme inhibitors. - HTS techniques have become an important part of the drug discovery process allowing researchers to sift through massive libraries of compounds to find ‘hits’ that are active against a therapeutic target of interest.
This latest research, published as an early view article in the journal Analytical Chemistry by researchers from the Discovery Technologies and Diabetes and [...]
Novartis weighs up label-free HTS for drug discovery - Researchers from Novartis have published results using high-throughput screening (HTS) mass spectrometry (MS) techniques for the identification of enzyme inhibitors.
HTS techniques have become an important part of the drug discovery process allowing researchers to sift through massive libraries of compounds to find ‘hits’ that are active against a therapeutic target of interest.
This latest research, published [...]
Cisbio has entered into a partnership agreement with Lumiphore to gain access to new fluorescence reporter molecules for use in its high throughput (HT) screening assays. - The agreement grants Cisbio exclusive access to the Lumi4 compounds for fluorescence applications in drug discovery, with Lumiphore free to develop partnerships to develop the technology in other areas.
Cisbio has played an important part in the development of HT drug screening technologies and has enabled researchers to conduct binding assays based on its homogenous time-resolved [...]
Cisbio international’s upcoming third annual “HTRF® In Drug Discovery” Symposium will be held September 26-28 in Sonoma, California - Over the course of three days, experts in drug screening from around the globe will assemble to discuss the latest applications of Cisbio’s proprietary HTRF® technology in the drug screening, target discovery and mechanistic fields. A number of scientific sessions will specifically examine GPCR and kinase screening, cell-based biomarker detection [...]
DiscoveRx, a Leader in GPCR Assays, Launches a 30 Second Assay for Beta-Arrestin Based ScreeningWith the PathHunter(TM) Flash Detection Kit - DiscoveRx, a Leader in GPCR Assays, Launches a 30 Second Assay for Beta-Arrestin Based ScreeningWith the PathHunter(TM) Flash Detection Kit, beta-arrestin recruitment by a GPCR can now be detected in 30 seconds, permitting screens of up to 1,000,000 compounds in 48 hours. Unlike lengthy reporter gene assays, PathHunter beta-arrestin assays are direct and hence minimize [...]
Shrinking screening for drugs - Scientists in the US have found a way to screen for potential drugs using just minuscule amounts of chemical reagents.
Brian Cunningham and Charles Choi at the University of Illinois at Urbana-Champaign have designed a 96-well microplate that reduces the volume of precious chemicals needed to perform a drug screening assay.
This is no run of the [...]
KU Medical Center to lead $7.5-million male contraceptive research and drug development program - A researcher at the University of Kansas Medical Center has been awarded more than $7.5 million in funding from the National Institutes of Health to lead a team, including researchers at seven universities, in a collaborative effort to develop male contraceptives.
This five-year grant will establish the Interdisciplinary Center for Male Contraceptive Research and Drug [...]
Advancing the Science of Drug Discovery: Bridging Research & Development - Society for Biomolecular Sciences
Presents its 13th Annual Conference & Exhibition
Advancing the Science of Drug Discovery: Bridging Research & Development
April 15-19, 2007
Palais Des Congres de Montréal
Montréal, Canada
After the Society’s most successful annual event in Seattle this year, professionals from around the globe will want to participate in the next SBS Annual Conference & Exhibition in April [...]
NEXUS Biosystems’ Universal Store Compound Management System Selected as Key Component of Vanderbilt University’s High-Throughput Screening Facility - POWAY, CALIF., January 11 /CNW/ - NEXUS Biosystems announced that
Vanderbilt University's High-Throughput Screening (HTS) Facility has selected
the Universal Store to manage its ever-growing collection of synthetic small
molecules and natural products. The Universal Store will serve as the main
repository for maintaining and managing Vanderbilt's collection as a part of
its basic research and translational drug discovery activities. [...]
Compatibility of Cell-Based Assays with High-Throughput Screening Proving to Be a Key Challenge - DUBLIN, Ireland–(BUSINESS WIRE)–Research and Markets has announced the addition of “Development of Cell-Based Assays (Technical Insights)” to their offering.
This Frost & Sullivan research service titled Developments in Cell Based Assays focuses on the technological [...]
BioTrove Screens Two Million Samples Using RapidFire Lead Discovery, a Label Free High-Throughput Mass Spectrometry Platform for Intractable Drug Targets; Four Clients to Present Data at Upcoming Society for Biological Sciences Meeting - WOBURN, Mass.–(BUSINESS WIRE)–Sep 12, 2006 - BioTrove, Inc. announced today the successful screening of more than two million individual samples using their RapidFire(TM) Lead Discovery System. RapidFire(TM) is a unique, mass spectrometry-based, high-throughput screening platform that facilitates label-free screening of challenging drug targets using native substrates.
BioTrove currently provides screening services and instrumentation to nine large [...]
Frost & Sullivan Recognizes DiscoveRx’s Innovative Assay Technology for Drug Screening and Overall Achievements in Intact Cell-Based Assays - PALO ALTO, Calif., Sept. 7 /PRNewswire/ — Frost & Sullivan selected DiscoveRx Corp. as the recipient of the 2006 Frost & Sullivan Award for Technology Innovation for its development of the PathHunter(TM), an innovative protein trafficking platform technology. In its simplest format, this assay system allows users to monitor signaling pathways using translocation in [...]
Discover the Latest Improvements to Compound Screening In Pharmaceutical Research and Chemical Biology - Throughput Screening in Drug Discovery - DUBLIN, Ireland–(BUSINESS WIRE)–Sep 19, 2006 - Research and Markets (http://www.researchandmarkets.com/reports/c42217) has announced the addition of High-Throughput Screening in Drug Discovery to their offering.
This book is designed as a professional guide for successful compound screening in pharmaceutical research and chemical biology. It discusses the rationale behind successful and “intelligent” screening approaches and presents current methods and [...]
Institut Pasteur Korea Selects ActivityBase™ as its Screening Solution of Choice - IDBS has announced that Institut Pasteur - Korea has implemented the ActivityBase data management software suite to increase efficiency and throughput in its screening operations.
Institut Pasteur Korea (IP-K), a Research Center located in Seoul, South Korea, has purchased ActivityBase to handle their biology and chemistry data for High Throughput and High Content Screening (HTS/HCS).
IP-K is implementing HCS [...]
EpiCept Announces IND Filing of Novel Compound with Potent Apoptotic and Tumor Selective Vascular Disruptive Activity for Treatment of Cancer - NGLEWOOD CLIFFS, New Jersey, October 2 /PRNewswire/ – - EPC2407 Latest Clinical Candidate from Company’s Apoptosis ScreeningTechnology EpiCept Corporation (Nasdaq: EPCT; OMX Stockholm) today announced that ithas submitted an investigational new drug (IND) application to the U.S. Foodand Drug Administration (FDA) to begin Phase I clinical studies of EPC2407 incancer patients. EPC2407 [...]
AnaSpec Develops Industry’s Only HTS Assay Kits for Screening HCV NS3/4A - San Jose, CA - July 6, 2006
Hepatitis C virus (HCV), belonging to the Flaviviridae family of positive, single stranded RNA, infects approximately 170 million people worldwide (1). The HCV polyprotein consists of structural proteins (C, E1, E2 and p7), and the non-structural (NS) proteins (NS2, NS3, NS4A, NS4B, NS5A, and [...]
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