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BioScreening - organic compounds for screening
HT Screening NewsGTCbio Announces 4th Annual Assay Development and Screening Conference taking place June 8-9, 2009. - San Francisco, CA - GTCbio Announces its 4th Annual Assay Development and Screening Conference taking place June 8-9, 2009. As compounds derived from high throughput screening increasingly find their way into clinical trials, drug screening has become widely accepted as a critical step in the drug discovery process. After more than a decade of rapid [...]
Fragment Based Screening Service at CRELUX and ZoBio - Munich (D) and Leiden (NL), November 24, 2008 / b3c newswire / – CRELUX and ZoBio announced today that they have successfully executed their first fragment based screening projects from a jointly established platform.
One of the first targets, which also will be made accessible to customers, was Pim1, a kinase that has been implicated in [...]
Cell-Based Assays: Innovations in Reagents, Technologies & Screening October 23 - 24, 2008 - Cell-based assays provide one of the most valuable tools in drug discovery. They are routinely used in target validation, HTS campaigns, structure activity relationship analyses and ADMET studies. Many factors need to be considered in designing, developing and running relevant cell based assays to progress discovery programs. Significant advances continue to be made in assay [...]
Sanofi-aventis signs a collaboration agreement with RainDance Technologies and Louis Pasteur Univers - The FINANCIAL — Sanofi-aventis announced on September 26 the launch of the dScreen Consortium, a research initiative conducted with RainDance Technologies, Inc., Lexington, Massachusetts, and Louis Pasteur University, Strasbourg, France, to develop the next generation of High-Throughput Screening (HTS) for drug discovery applications.
The consortium was founded with the assistance of the Alsace BioValleyTM Cluster, France, which helped [...]
Idealp-Pharma launches « hit-to-candidate » services - Services to accelerate programs from biological target to first-in-man use Idealp-Pharma is launching fully integrated drug discovery and preclinical development services combining medicinal chemistry, cheminformatics,
screening, early ADMET and preclinical development capabilities to speed up
partner’s and client’s small molecules programs from biological target to firstin-
man use.
According to Serge Petit, PhD, President and CEO, “Being a one-stop-shop [...]
Genedata and Axxam Announce High Throughput Screening Data Analysis Collaboration - Genedata and Axxam have signed a multi-year contract for the implementation of the Genedata Screener® data analysis and management platform into Axxam’s high throughput screening process.
Genedata, the leading provider of in silico solutions for the pharmaceutical and life science industries, and Axxam, a leading biotechnology research organization offering early-stage discovery research services for the life [...]
4th Annual International Conference on Compound Libraries - in Dusseldorf, Germany from 6th to 8th October 2008. - From Focused Compound Libraries to optimised Hit-to-Lead - that’s the motto of IQPC’s 4th international conference on “Compound Libraries” (formerly “Focused Compound Libraries”). Nowadays the pharmaceutical industry is under enormous pressure, and the key for the industry to survive is faster and more efficient drug discovery. To improve their lead generation process and library, pharmaceutical [...]
Direct Screening of Natural Products Extracts Using Mass Spectrometry - Present advances in screening and separation technologies reveal extracts bioactivity with great efficiency and accuracy. Recently reported method of Direct Screening of Natural Products Extracts Using Mass Spectrometry does not require any preparation or fractionation work. Several hundred crude extracts can be screened per one day. Direct bioaffinity screening mass spectrometry method followed by the [...]
Spermatech Selects Evotec as Partner for High-Throughput Screening and Lead Discovery - HAMBURG, Germany and OXFORD, England and OSLO, March 12, 2008 /PRNewswire-FirstCall/ — Evotec AG announced today that Spermatech A/S has chosen them as a partner to identify small molecule therapeutics for their pharmaceutical discovery project.
Through the study of the physiology of sperm motility, more specifically of “rapid swimmers” that cause fertilisation, Spermatech have identified biological [...]
US Plans Use of Automated Toxicity Screening, Could End Animal Testing - Federal scientists are collaborating on a new approach to testing the toxicity of chemicals ranging from pesticides to household cleaners. They plan to use new automated high-speed cell tests to get more reliable data faster and more cheaply, and with less reliance on animal testing.
The National Institutes of Health and the U.S. Environmental Protection Agency are partners [...]
High Throughput Screening 2007: HighTech Business Decisions Reports New Strategies, - SAN JOSE, Calif.--(Business Wire)--HTS laboratories continue to evolve their processes and strategies
to increase their success rates and improve efficiencies in their drug
discovery efforts. New strategies include the use of phenotypic and
pathway-based assays in primary or secondary screening, the use of new
targets and the expansion in the diversity of compounds screened for
new drug candidate leads. The [...]
Burnham Institute Selects Labcyte Acoustic Liquid Handling Technology - Sunnyvale, CA November 15, 2007 - Labcyte Inc. will supply Burnham Institute for Medical Research (Burnham) with more than $2.3 million worth of Echo® liquid handlers for use in screening large biological libraries. The systems will be installed at both the Institute’s LaJolla, (CA) and Lake Nona, Orlando (FL) campuses. These instruments will be part [...]
Researchers from Novartis have published results using high-throughput screening (HTS) mass spectrometry (MS) techniques for the identification of enzyme inhibitors. - HTS techniques have become an important part of the drug discovery process allowing researchers to sift through massive libraries of compounds to find ‘hits’ that are active against a therapeutic target of interest.
This latest research, published as an early view article in the journal Analytical Chemistry by researchers from the Discovery Technologies and Diabetes and [...]
Novartis weighs up label-free HTS for drug discovery - Researchers from Novartis have published results using high-throughput screening (HTS) mass spectrometry (MS) techniques for the identification of enzyme inhibitors.
HTS techniques have become an important part of the drug discovery process allowing researchers to sift through massive libraries of compounds to find ‘hits’ that are active against a therapeutic target of interest.
This latest research, published [...]
Cisbio has entered into a partnership agreement with Lumiphore to gain access to new fluorescence reporter molecules for use in its high throughput (HT) screening assays. - The agreement grants Cisbio exclusive access to the Lumi4 compounds for fluorescence applications in drug discovery, with Lumiphore free to develop partnerships to develop the technology in other areas.
Cisbio has played an important part in the development of HT drug screening technologies and has enabled researchers to conduct binding assays based on its homogenous time-resolved [...]
Cisbio international’s upcoming third annual “HTRF® In Drug Discovery” Symposium will be held September 26-28 in Sonoma, California - Over the course of three days, experts in drug screening from around the globe will assemble to discuss the latest applications of Cisbio’s proprietary HTRF® technology in the drug screening, target discovery and mechanistic fields. A number of scientific sessions will specifically examine GPCR and kinase screening, cell-based biomarker detection [...]
DiscoveRx, a Leader in GPCR Assays, Launches a 30 Second Assay for Beta-Arrestin Based ScreeningWith the PathHunter(TM) Flash Detection Kit - DiscoveRx, a Leader in GPCR Assays, Launches a 30 Second Assay for Beta-Arrestin Based ScreeningWith the PathHunter(TM) Flash Detection Kit, beta-arrestin recruitment by a GPCR can now be detected in 30 seconds, permitting screens of up to 1,000,000 compounds in 48 hours. Unlike lengthy reporter gene assays, PathHunter beta-arrestin assays are direct and hence minimize [...]
Shrinking screening for drugs - Scientists in the US have found a way to screen for potential drugs using just minuscule amounts of chemical reagents.
Brian Cunningham and Charles Choi at the University of Illinois at Urbana-Champaign have designed a 96-well microplate that reduces the volume of precious chemicals needed to perform a drug screening assay.
This is no run of the [...]
KU Medical Center to lead $7.5-million male contraceptive research and drug development program - A researcher at the University of Kansas Medical Center has been awarded more than $7.5 million in funding from the National Institutes of Health to lead a team, including researchers at seven universities, in a collaborative effort to develop male contraceptives.
This five-year grant will establish the Interdisciplinary Center for Male Contraceptive Research and Drug [...]
Advancing the Science of Drug Discovery: Bridging Research & Development - Society for Biomolecular Sciences
Presents its 13th Annual Conference & Exhibition
Advancing the Science of Drug Discovery: Bridging Research & Development
April 15-19, 2007
Palais Des Congres de Montréal
Montréal, Canada
After the Society’s most successful annual event in Seattle this year, professionals from around the globe will want to participate in the next SBS Annual Conference & Exhibition in April [...]
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