10th EFMC Short Course on Medicinal Chemistry April 12-15 2015, Oegstgeest, Netherlands
In 2009, EFMC launched a series of short courses aimed to favour cultural and scientific growth of the medicinal chemistry community and organized with affordable fees for participation. EFMC will continue the tradition in 2015, and is pleased to announce the following courses:
10th EFMC Short Course on Medicinal Chemistry
Small-Molecule Modulation of Protein-Protein Interactions (PPIs)
Oegstgeest (near Leiden), The Netherlands - April 12-15, 2015
This intensive course is intended for scientists working in the field, and the presentations will be given by senior scientists from industry and academia. The number of participants will be limited to 35, to favour in depth discussion.
COURSE OUTLINE
Protein-Protein Interactions (PPIs) lie at the heart of almost every physiological process and every disease. With a recently estimated number of 300,000 in humans, the possibilities for therapeutic intervention are significantly larger compared to ‘classical’ drug targets. While this potential is up to now largely untapped, some successful examples have shown that PPIs can be modulated by drug-like small molecules, natural products and peptides.
Specific features of PPIs as drug targets - in comparison to conventionally addressing e.g. enzymes - will be discussed, followed by a broad overview of the field, techniques to discover modulators of PPIs, and - in more detail - a number of case studies on successful PPI intervention will be presented. Speakers include a selection of top-scientists active in the field of PPI, both from industry and academia.
Course Organisers
Christian OTTMANN and Luc BRUNSVELD (TU Eindhoven, The Netherlands)
Local Organiser
Henk TIMMERMAN (VU University Amsterdam, The Netherlands)
Registration fee
€1.475 – including accommodation, breakfast, coffee breaks, lunches and dinners during the 3 days of the course
More information on registration can be found on www.efmcshortcourses.org
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