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Endotherm Life Science Molecules GmbH
Endotherm Life Science Molecules GmbH Science-Park II
D-66123 Saarbrucken Germany
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01.03.1999

Foundation of Endotherm GmbH at the Universitaet des Saarlandes in Saarbrücken, Germany

Development, manufacturing and distribution of flame retardants and fire proof coatings

since 2001

Contract Research and Custom Synthesis in Medicinal Chemistry and Process Research

since 2003

Internal drug discovery programmes
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Microscope Looks Into Cells of Living Fish
Sulfur Finding May Hold Key to Gaia Theory of Earth as Living Organism
Black Holes Turn Up the Heat for the Universe
Tiny Solar-Panel-Like Cells Help Restore Sight to the Blind
Why Inhibiting DNA Damage-Detecting Enzyme Is Effective in Fighting Cancer and Other Diseases
Pufferfish at the 'Beak' of Evolution: Why Humans Don't Continuously Replace Their Teeth
ScienceDaily (May 16, 2012) — Microscopes provide valuable insights in the structure and dynamics of cells, in particular when the latter remain in their natural environment. However, this is very difficult especially for higher organisms. Researchers of Karlsruhe Institute of Technology (KIT), the Max Planck Institute for Polymer Research, Mainz, and the American National Institutes of Health (NIH) have now developed a new method to visualize cell structures of an eighth of a micrometer in size in living fish larvae. Read the Full Story
ScienceDaily (May 15, 2012) — Astrophysicists have just discovered a new heating source in cosmological structure formation. Until now, astrophysicists thought that super-massive black holes could only influence their immediate surroundings. A collaboration of scientists at the Heidelberg Institute for Theoretical Studies (HITS) and in Canada and the US have now discovered that diffuse gas in the universe can absorb luminous gamma-ray emission from black holes, heating it up strongly. This surprising result has important implications for the formation of structures in the universe. Read the Full Story
ScienceDaily (May 15, 2012) — Astrophysicists have just discovered a new heating source in cosmological structure formation. Until now, astrophysicists thought that super-massive black holes could only influence their immediate surroundings. A collaboration of scientists at the Heidelberg Institute for Theoretical Studies (HITS) and in Canada and the US have now discovered that diffuse gas in the universe can absorb luminous gamma-ray emission from black holes, heating it up strongly. This surprising result has important implications for the formation of structures in the universe. Read the Full Story
ScienceDaily (May 13, 2012) — Using tiny solar-panel-like cells surgically placed underneath the retina, scientists at the Stanford University School of Medicine have devised a system that may someday restore sight to people who have lost vision because of certain types of degenerative eye diseases. Read the Full Story
ScienceDaily (May 10, 2012) — A new study published in Science May 11 is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other diseases. Read the Full Story
ScienceDaily (May 14, 2012) — Prickly pufferfish could hold the key to why humans do not continually replace their teeth and may lead to advances in dental therapies. Read the Full Story
image Microscope Looks Into Cells of Living Fish
image Sulfur Finding May Hold Key to Gaia Theory of Earth as Living Organism
image Black Holes Turn Up the Heat for the Universe
image Tiny Solar-Panel-Like Cells Help Restore Sight to the Blind
image Why Inhibiting DNA Damage-Detecting Enzyme Is Effective in Fighting Cancer and Other Diseases
image Pufferfish at the 'Beak' of Evolution: Why Humans Don't Continuously Replace Their Teeth

BioScreening News

  • Evotec Becomes First European CRO to Offer Agilent’s RapidFire Screening Tool
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  • IntelligentMDx Wins CE Mark for Group B Strep Assay on Abbott m2000 Instrument
    IntelligentMDx received a CE Mark for its qualitative Group B Streptococcus (GBS) in vitro diagnostic, IMDx GBS, for use on the Abbott m2000™ system. The assay is used to screen for Group B Streptococcus infection in at-risk pregnant women and women in labor. The real-time PCR test can be carried...
  • Admescope to Provide PlexPress Multiplex CYP Gene Expression Analysis Technology
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  • Six Suitors Join Bristol-Myers in Considering a Bid for Amylin
    After turning down an unsolicited bid from Bristol-Myers Squibb (BMS) in February, Amylin Pharmaceuticals is preparing to weigh offers from BMS and up to six other potential suitors. Citing unnamed “people familiar with the matter,” Bloomberg News reported that BMS has joined AstraZeneca, Merck & Co., Pfizer, Roche, Sanofi, and...
  • Accelr8, Denver Health Win $2M to Develop Battlefield Infections Diagnostic
    Accelr8 and Denver Health received notification that the Defence Medical Research and Development Program (DMRPD) has recommended a $2 million award to support a three-year project focused on developing a rapid diagnostic system for wound infections and serious infections secondary to trauma. The project was the sole recipient of funds...
  • Gamida Cell Raises $10M to Progress Phase III-Stage Hematologic Cancer Cell Therapy
    Gamida Cell raised $10 million through an internal Series E financing round with all its existing major shareholders. The proceeds will be used to support global commercialization of the firm’s Phase III-stage StemEx cord blood stem cell therapy for blood cancers, and continue development of additional pipeline candidates, including clinical...
  • ALS Institute, Neurotune to Evaluate Amyotrophic Lateral Sclerosis Therapeutic Candidate
    The ALS Therapeutic Institute and Neurotune established a collaboration to evaluate one of the latter’s neuromuscular diseases candidates in an ALS disease model. ALS is associated with motor neurons and their axons becoming disconnected from muscle, and Neurotune has identified a class of compounds designed to maintain neuromuscular junction strength...
  • KineMed, CHDI Ally on Biomarkers of Huntington Disease Progression, Drug Efficacy
    CHDI Foundation and KineMed established a collaboration to exploit the latter’s tandem mass spectrometry-based proteomics platform to analyze the in vivo dynamics of mutant huntingtin protein as a means of assessing Huntington disease progression and measuring the efficacy of therapeutic candidates. The aim is to generate data that will both...

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