Medicinal Chemistry in the 21st Century is facing both unprecedented opportunities and challenges. The 2011 Zing Medicinal Chemistry Conference brings together leading drug designers from industry and academia to discuss innovative approaches to success. The conference program has been created around five key themes that cover the scientific, technological and operational tools modern medicinal chemists need to design both efficiently and effectively: * Design Space: new thinking in multi-objective design, tactics to reduce toxicity risk and optimize ADME and CNS properties. * Allosteric modulation: New opportunities for GPCRs, kinases, ion channels and enzymes. * Pharmacodynamics: Exploiting binding kinetics and thermodynamics in design of best-in-class compounds. * Operational Space: increasing productivity through agile management, out-sourcing and open innovation approaches. * Emerging concepts and method in drug discovery: fragment-based drug design, chemoproteomics, polypharmacology.