PRESENTED BY: Dr. Jonathan Rosenberg, Corporate Development, IMGENEX Corporation
DATE & TIME:  September 1, 2010 (Wednesday) at 8:00 AM and 10:00 AM Pacific Time

OVERVIEW
This initial webinar will present research applications for reagents to Toll-like Receptors and other related products which are part of the extensive IMGENEX TLRSystem™ product portfolio. Topics include:

• Toll-Like Receptor Family Overview
• TLR Phenotyping by Flow Cytometry
• Dendritic Cell - T Cell Immunoregulatory Network
• TLR Signaling Pathways
• TLR Screening Techniques using TLR/NF-kB SEAPorter™ stable reporter cell lines

The webinar is designed to provide useful information for individuals involved in studying immune and inflammation signaling pathways utilizing a variety of platforms.

ABSTRACT
Toll-like Receptors (TLRs) sense microbial and host pattern antigens and initiate immune response cascades through NF-kB and IRF signaling pathways. Analysis of Toll-like Receptors, MyD88 and adaptor molecules of the NF-kB pathway, Pro-Inflammatory Cytokines and CD Markers provides opportunity for in depth understanding of the cells and pathways bridging Innate and Adaptive Immune Responses. Our studies will be presented as models for screening systems for new TLR ligand identification and their role in inflammation and immune cell signaling pathways.