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Rapp Polymere
TentaGel resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted. As PEG is a "cameleon type" polymer with hydrophobic and hydrophilic properties, the graft copolymer shows modified physico chemical properties. There are in principle two ways to introduce PEG onto the modified polystyrene matrix. The simplest immobilization procedure is to couple PEG via one of its terminal hydroxyl groups to chloromethylated polystyrene according to the classical ether synthesis or to use other bifunctional PEG's for coupling onto the solid support.
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