LOPAC1280™

LOPAC1280™: A Versatile Library for Assay Validation and High Throughput Screening

Improve screening efficiency with the newly expanded version of the Sigma-RBI Library of Pharmacologically Active Compounds. Like its predecessor (LOPAC640™), LOPAC1280™ allows you to validate your high throughput screening assays with high purity, small organic ligands with well documented pharmacological activities. The addition of compounds in areas such as apoptosis and phosphorylation broaden the application range of LOPAC1280™ to assays dealing with the hottest areas of Cell Signaling & Neuroscience research.

Save time and money by reducing the number of false leads from your screen.

Guide secondary screening of larger, more diverse libraries by using compounds with pharmaceuticallyrelevant structures.

Explore the activity of well-characterized compounds directed at orphan receptors.

LOPAC1280™ Library of Pharmacologically-Active Compounds Prod. No. LO1280 (Please refer to Prod. No. LO3300 outside the US)

Easy-to-use collection of well-characterized, small organic ligands

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 µl at 10 mM in DMSO).

Updated and expanded to include the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

◆ Antibiotics
◆ Gene Regulation & Expression
◆ Multi-Drug Resistance
◆ Apoptosis
◆ Ion Channels
◆ Neurotransmission
◆ Calcium Signaling
◆ Lipid Signaling
◆ Phosphorylation

SD File* Provided to Construct a Database Containing:
◆ Structure
◆ Primary Name
◆ Rack Position
◆ Pharmacological Activity
◆ Secondary Name
◆ Sigma-RBI Product Number

*Technical information for each compound is provided in standard SD file format for use with ISIS/Base or other compatible software (software not provided).

For additional information, please visit LOPAC 1280™