Compound-Libraries

BioScreening.net » Compound Libraries

• Natural compounds derived from plants could yield hundreds of new drugs
  NYBG scientist says the plant world has “great potential” as a source of new medicines There are probably at least 500 medically useful chemicals awaiting discovery in plant species whose chemical constituents have not yet been evaluated for their potential to cure or treat disease, according to a new analysis by a New York Botanical [...]
  
  
• Accessing Nuclear Receptors with ActiTarg-N
  TimTec adds new targeted library to its ActiTarg Series. ActiTarg-N gathers 1040 nuclear receptors ligands analogs. Nuclear receptors are inside-cell proteins that regulate gene transcription and affect wide range of biological functions throughout organism normal and pathological development. These are the super-family of 48 structurally related transcription factors that can be regulated by small molecules. [...]
  
  
• Fragment Library
  Thermo Fisher Scientific Inc. announced that its Maybridge Ro3 Diversity Fragment Library has helped researchers validate an emerging technique for drug discovery that targets key protein receptors involved in a wide range of biological functions. David Myszka, founder of Biosensor Tools LLC and director of the Center for Biomolecular Interaction Analysis at the University of [...]
  
  
• Jet Lag Pill to Slow Down Body Clock
  Scientists are one step closer to developing a jet lag pill that could relieve millions of long-haul passengers from sleepless nights and mid-afternoon drowsiness. Using automated screening techniques developed by pharmaceutical companies to find new drugs, researchers from UC San Diego and three other research institutions have discovered a molecule with the most potent effects [...]
  
  
• Molecular Target for Screening: G-Protein-Coupled Receptors
  Newark, DE. August, 2010 – Press Release – TimTec, LLC. – Molecular Target for Screening:  G-Protein-Coupled Receptors, ActiTarg-G G-Protein-Coupled Receptors are the largest gene families in the human genome and, rightfully so, have become the leading molecular target in 2008. In 2009 SBS April meeting in Lille, France, followed-up with screening trends report stating that  [...]
  
  
• Evotec Gains Access to Hypha’s MycoDiverse Natural Products Library
  Evotec negotiated access to U.K.-based Hypha Discovery’s MycoDiverse™ fungi-derived natural product screening library. The deal means Evotec will be able to offer the library to clients through its hit and lead identification services. Hypha currently has access to over 2,500 strains of higher basidiomycete and ascomycete fungi, many from South American and South East Asian [...]
  
  
• Product Focus: Automated Liquid Handling
  Automated liquid handlers encompass a range of instruments and systems whose function is to dispense liquids rapidly, usually in very small quantities, at user-specified volumes, and with great accuracy, precision, and reproducibility. Liquid handlers are sold in a variety of fluid-dispensing configurations, from single-channel through eight (one row of a 96-well microtiter plate), 96, and [...]
  
  
• Developments in Focused Kinase Libraries
  Chemical libraries have long been a mainstay in the search for new pharmaceutical compounds, and they have been created using many different paradigms. Vast diverse collections of unique compounds have been screened at high throughput to find appropriate effects on target proteins. Such large libraries continue to be used for drug discovery, but screening smaller, [...]
  
  
• Computational Method Points To New Uses, Unexpected Side Effects Of Already Existing Drugs
  Scientists at the University of North Carolina at Chapel Hill School of Medicine and the University of California, San Francisco have developed and experimentally tested a technique to predict new target diseases for existing drugs. The researchers developed a computational method that compares how similar the structures of all known drugs are to the naturally [...]
  
  
• Trophos launches the new generation of its fast plate imaging instrument, the Plate RUNNER HD
  Marseille, FRANCE, 2009 September 29 – Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics for indications with under-served needs in neurology and cardiology, announced today the launch of the new generation of its fluorescence fast plate imaging system, the Plate RUNNER HD(R). Trophos originally developed the Plate RUNNER HD(R) to speed up its [...]